NAD (Nicotinamide adenine dinucleotide) is a vital coenzyme that is essential to cellular function. It facilitates the transfer of energy within cells along with a host of other metabolic functions.
Vitamins are organic compounds that the body needs to function. There are many forms of vitamin B- each chemically unique with different essential roles in the body. Vitamin B3, specifically, is a precursor to NAD+.
No. Niacin is another name for Vitamin B3. Vitamin B3 consists of 3 separate organic compounds: nicotinic acid, or NA, nicotinamide, or Nam, and nicotinamide riboside, or NR. All three of these components are eventually converted to NAD+ and for this reason are considered NAD+ precursors.
NAD+ is an essential component of the citric acid cycle (or Krebs cycle), a cellular process that produces energy for every cell in the body. It participates in energy production by interacting with oxygen in mitochondria to produce the fuel the body needs to function: a protein called ATP. NAD+ is also an essential cofactor of key enzymes responsible for longevity called sirtuins. Sirtuins are found to be important regulators of genes thought to be important with regards to lifespan.
• NAD+ has been used in a variety of different clinical scenarios. NAD+ has been reported to be beneficial with regards to increased energy, enhanced mood, improved sleep, decreased stress and anxiety, PTSD and depression, increased immunity, hydration, and improved exercise recovery.
NAD+ may also strengthen hair, nails and skin while slowing the aging process.
• NAD+ has also been used in the treatment of a number of chronic illnesses: Fibromyalgia, Alzheimer’s disease, CTE (Chronic traumatic Encephalopathy), Chemo brain, MS and Parkinson's disease.
• NAD+ is commonly used as part of addiction recovery programs for alcoholism, opioid and Benzodiazepine Dependence.
• Aging results in lower NAD+ levels, and as a result, chronic NAD+ supplementation is thought to be important in combating the aging process.
Nicotinamide riboside is believed to be safe with few — if any — side effects. In Human studies, taking 1,000–2,000 mg per day was not associated with harmful effects ( 28 , 29 ). Rarely people have reported nausea, fatigue, headaches, diarrhea, stomach discomfort and indigestion ( 30 ).
No. Oral supplements of NAD+ do exist. Unfortunately many oral medications are subject to breakdown before entering the blood stream, and NAD+ is known to be broken down by cells that line the intestines.
NAD+ is thought to strengthen hair, nails, and skin by slowing normal aging processes. Emerging evidence implicates that elevation of NAD+ levels may slow or even reverse the aspects of aging and also delay the progression of age-related diseases.
NAD+ is constantly being used by the body. Chronically maintaining higher NAD levels likely requires periodic infusions. Addiction recovery programs typically involve daily high dose infusions for weeks at a time. Ask about our weekly chronic maintenance packages. Custom regimens can be tailored to your needs by request.